Panama City 5 Star Hotels

Not Just Any Hotel – Only the Best Panama City 5 Star Hotels, Selected for You!

Panama City

Mar 29, 2025 - Mar 30, 2025

2 adults, 1 room

Find

Tourist VR

Panama Hotels

Panama City 5 Star Hotels

Price per night: Price / night

Up to $100

$100 - 200

From $200

Rating: Guest rating

Excellent 9+

Very good 8+

Good 7+

All ratings

Star rating: Star rating

5-stars

4-stars

3-stars

Unrated

8.4

Very good (118)

Sortis Hotel, Spa & Casino, Autograph Collection

View map · 0.5 mi City Centre

From

109US$ /per night

8.2

Very good (146)

W Panama

View map · 1.1 mi City Centre

From

147US$ /per night

8.4

Very good (425)

Radisson Hotel Panama Canal

View map · 4.4 mi City Centre

From

75US$ /per night

8.4

Very good (95)

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

View map · 5.2 mi City Centre

From

157US$ /per night

8.2

Very good (180)

Novotel Panama City

View map · 0.4 mi City Centre

From

65US$ /per night

8.4

Very good (190)

Hilton Panama

View map · 1.3 mi City Centre

From

125US$ /per night

8.4

Very good (367)

Plaza Paitilla Inn

View map · 1.4 mi City Centre

From

67US$ /per night

8.4

Very good (110)

Waldorf Astoria Panama

View map · 1.3 mi City Centre

From

125US$ /per night

8.2

Very good (166)

Hotel Las Americas Golden Tower Panama

View map · 1.1 mi City Centre

From

84US$ /per night

8.2

Very good (80)

Aloft Panama

View map · 1.2 mi City Centre

From

92US$ /per night

8.4

Very good (216)

Summit Rainforest Golf Resort & All Inclusive

View map · 8.7 mi City Centre

From

36US$ /per night

8.6

Excellent (118)

Ac Hotel By Marriott Panama City

View map · 0.9 mi City Centre

From

89US$ /per night

8.2

Very good (279)

Marinn Place Financial District

View map · 1.0 mi City Centre

From

75US$ /per night

8.2

Very good (60)

Amarla Boutique Hotel Casco Viejo

View map · 3.1 mi City Centre

From

518US$ /per night

8.2

Very good (146)

Hotel Mio Panama

View map · 0.9 mi City Centre

From

66US$ /per night

8.2

Very good (3)

Yoo Panama

View map · 1.3 mi City Centre

From

127US$ /per night

8.2

Very good (118)

Sheraton Grand Panama

View map · 1.2 mi City Centre

From

144US$ /per night

8.2

Very good (127)

American Trade Hotel

View map · 3.2 mi City Centre

From

234US$ /per night

8.2

Very good (290)

Selina Casco Viejo Panama City

View map · 3.2 mi City Centre

From

40US$ /per night

Very good (194)

Grand International Hotel

View map · 0.7 mi City Centre

From

36US$ /per night

7.8

Very good (98)

Studio Coliving Hotel

View map · 1.1 mi City Centre

From

40US$ /per night

8.2

Very good (357)

Hotel Montreal

View map · 1.4 mi City Centre

From

25US$ /per night

8.2

Very good (200)

Hotel Coral Suites

View map · 0.8 mi City Centre

From

53US$ /per night

8.4

Very good (108)

Le Meridien Panama

View map · 1.3 mi City Centre

From

120US$ /per night

8.4

Very good (215)

Global Hotel Panama

View map · 0.7 mi City Centre

From

85US$ /per night

8.4

Very good (326)

Best Western Plus Panama Zen Hotel

View map · 0.5 mi City Centre

From

71US$ /per night

Very good (9)

Waymore Hotel Spa & Casino

View map · 0.9 mi City Centre

From

106US$ /per night

8.4

Very good (225)

Central Hotel Panama Casco Viejo

View map · 3.1 mi City Centre

From

155US$ /per night

7.6

Very good (171)

Hotel Bahia Suites

View map · 2.2 mi City Centre

From

60US$ /per night

8.4

Very good (445)

Decapolis Hotel Panama City

View map · 1.2 mi City Centre

From

71US$ /per night

8.2

Very good (190)

Albrook Inn

View map · 3.0 mi City Centre

From

75US$ /per night

8.4

Very good (246)

Magnolia Inn

View map · 3.1 mi City Centre

From

13US$ /per night

8.2

Very good (218)

Victoria Hotel And Suites Panama

View map · 0.9 mi City Centre

From

48US$ /per night

8.4

Very good (113)

Holiday Inn Panama Distrito Financiero, An Ihg Hotel

View map · 0.8 mi City Centre

From

66US$ /per night

8.4

Very good (209)

Intercontinental Miramar Panama, An Ihg Hotel

View map · 1.4 mi City Centre

From

124US$ /per night

8.2

Very good (73)

La Concordia - Boutique Hotel

View map · 3.1 mi City Centre

From

334US$ /per night

8.8

Excellent (6)

Hotel San Felipe

View map · 3.1 mi City Centre

From

118US$ /per night

8.2

Very good (239)

Hotel Casa Panama

View map · 3.0 mi City Centre

From

73US$ /per night

8.6

Excellent (97)

Bodhi Panama City

View map · 1.0 mi City Centre

From

15US$ /per night

8.6

Excellent (63)

Residence Inn By Marriott Panama City

View map · 1.2 mi City Centre

From

131US$ /per night

8.2

Very good (116)

Torres De Alba Hotel & Suites

View map · 1.0 mi City Centre

From

93US$ /per night

7.8

Very good (27)

Hostel-Island Paradise, Saboga Lodge And Villa Noelia (Adults Only)

View map · 40.2 mi City Centre

From

71US$ /per night

8.2

Very good (393)

Tryp By Wyndham Panama Centro

View map · 0.9 mi City Centre

From

77US$ /per night

8.4

Very good (54)

La Isabela Suites

View map · 3.1 mi City Centre

From

167US$ /per night

8.4

Very good (72)

Hostal Loco Coco Loco

View map · 0.9 mi City Centre

From

13US$ /per night

8.2

Very good (77)

Eurohotel

View map · 1.8 mi City Centre

From

33US$ /per night

8.2

Very good (48)

Hotel Acapulco

View map · 2.3 mi City Centre

From

33US$ /per night

8.2

Very good (228)

Hotel Ojos Del Rio

View map · 1.7 mi City Centre

From

43US$ /per night

8.2

Very good (258)

Hotel Terranova

View map · 1.3 mi City Centre

From

37US$ /per night

8.2

Very good (309)

The Executive Hotel

View map · 1.0 mi City Centre

From

72US$ /per night

8.2

Very good (194)

Hotel Marbella

View map · 0.8 mi City Centre

From

34US$ /per night

8.4

Very good (194)

Hotel Caribe Panama

View map · 2.3 mi City Centre

From

41US$ /per night

7.2

Good (44)

Hotel Benidorm Panama

View map · 2.3 mi City Centre

From

35US$ /per night

8.2

Very good (190)

Riande Urban Hotel

View map · 0.7 mi City Centre

From

44US$ /per night

8.2

Very good (120)

Gran Evenia Panama Hotel

View map · 0.9 mi City Centre

From

94US$ /per night

8.4

Very good (144)

Hotel Casa Miller

View map · 2.6 mi City Centre

From

50US$ /per night

8.4

Very good (60)

Hotel California Panama

View map · 1.6 mi City Centre

From

32US$ /per night

8.2

Very good (324)

Hotel Costa Inn

View map · 1.8 mi City Centre

From

33US$ /per night

8.2

Very good (138)

Holiday Inn Panama Canal, An Ihg Hotel

View map · 4.2 mi City Centre

From

85US$ /per night

8.2

Very good (125)

The Balboa Inn

View map · 3.6 mi City Centre

From

36US$ /per night

Discover Your Perfect Stay

Panama City, a vibrant metropolis that seamlessly blends rich history with modern elegance, is a traveler's paradise. As you explore the city's stunning skyline and captivating culture, you’ll undoubtedly seek out accommodations that match the allure of your surroundings. For those in search of an opulent stay, the 5 star hotels in Panama offer unparalleled luxury and comfort, promising an unforgettable experience.

From the moment you step into one of Panama City's premium hotels, you'll be greeted by world-class service and exquisite amenities. Whether you desire a room with breathtaking views of the Panama Canal or a serene spa retreat to unwind after a day of exploration, these hotels cater to every whim. Notably, properties like the renowned American Trade Hotel and the stunning Hard Rock Hotel embody the essence of luxury and are perfect choices for discerning travelers.

Beyond the lavish accommodations, 5 star hotels in Panama also provide unique dining experiences that highlight the diverse culinary scene of the city. Guests can savor gourmet dishes crafted by award-winning chefs, showcasing both local flavors and international influences. With such exceptional offerings, it's clear that choosing one of these top-tier hotels not only elevates your stay but also enriches your overall experience in Panama City.

Name of hotel	Accommodation Rating	Price, $
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City	9.3 / 10 (558 Reviews)	From 157US$
W Panama	8.6 / 10 (600 Reviews)	From 163US$
Sofitel Legend Casco Viejo, Panama City	9.5 / 10 (697 Reviews)	From 326US$
American Trade Hotel	8.8 / 10 (607 Reviews)	From 291US$

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Santa Maria Boulevard

For travelers seeking a blend of luxury and recreation, The Santa Maria, A Luxury Collection Hotel & Golf Resort is a premier choice among the 5 star hotels in Panama. This exquisite hotel features a stunning golf course designed by renowned architect Nicklaus Design, providing a unique experience for golf enthusiasts. Guests can enjoy elegantly decorated rooms and suites with upscale amenities and breathtaking views of the surrounding landscapes. The hotel also features multiple dining options, including a gourmet restaurant serving international cuisine, which enhances the overall experience of staying here. The Santa Maria offers a luxurious spa and wellness center, perfect for relaxation after a day of exploration or golf. This hotel is ideal for those looking to elevate their stay with both comfort and adventure in Panama City.

From

157US$ /per night

W Panama

Calle 50 And Aquilino De La Guardia

W Panama stands out as one of the most stylish 5 star hotels in Panama, perfectly situated in the very heart of the financial district. With a modern design that reflects the vibrant culture of the city, this hotel provides a trendy urban escape for visitors. Guests can enjoy spacious rooms equipped with state-of-the-art technology, alongside stunning views of the Panama skyline. The hotel features an impressive rooftop bar, which is perfect for evening cocktails while soaking in mesmerizing city vistas. Additionally, W Panama is known for its excellent dining options and a lively atmosphere, making it a hotspot for both locals and tourists. This hotel embodies the essence of contemporary luxury, ensuring an unforgettable stay in Panama City.

From

163US$ /per night

5 Star Hotels in Panama

When planning a visit to Panama City, choosing the right place to stay is essential to enhancing your experience. The city is renowned for its exceptional 5 star hotels, each offering a unique blend of luxury, comfort, and unparalleled service. From stunning skyline views to gourmet dining options, these hotels cater to discerning travelers seeking the ultimate indulgence. Whether you're here for business or leisure, the following selections of 5 star hotels in Panama promise to provide you with a memorable stay. It’s time to immerse yourself in the lavish surroundings and world-class amenities that make Panama City a top destination. Read on to discover some of the best 5 star hotels that the city has to offer.

Sofitel Legend Casco Viejo, Panama City

Calle Primera Oeste San Felipe Casco Viejo

Sofitel Legend Casco Viejo epitomizes sophisticated luxury, making it one of the premier 5 star hotels in Panama. Located in the historic Casco Viejo district, this hotel blends modern amenities with a rich, cultural heritage. Guests can relax in beautifully appointed rooms with elegant décor and views of the picturesque streets or the Pacific Ocean. The hotel also boasts a stunning infinity pool overlooking the city, as well as a premier restaurant that highlights local gastronomy. With impeccable service and a focus on personalized experiences, Sofitel Legend Casco Viejo ensures that every guest feels like royalty. The ambiance and architectural beauty make it a must-visit for those seeking a luxurious stay in Panama City.

From

326US$ /per night

American Trade Hotel

Plaza Herrera, Casco Viejo

American Trade Hotel combines cultural charm with modern conveniences, making it a unique option among the 5 star hotels in Panama. Nestled in the historic Casco Viejo, this beautifully restored hotel preserves the architectural heritage of the area while offering contemporary comfort. Guests can enjoy stylish rooms adorned with local artwork and luxurious furnishings, alongside access to vibrant common areas and a relaxing rooftop terrace. The hotel's onsite restaurant serves delicious culinary creations that reflect the local flavors and ingredients, making dining a delightful experience. Additionally, the American Trade Hotel hosts various cultural events and exhibitions, enriching the stay with a deeper connection to Panama’s heritage. This hotel offers a blend of luxury, history, and local culture, making it a standout choice for discerning travelers.

From

291US$ /per night

Other city in World

• Newport

• Macon

• Grand Rapids

• Split

• Bordeaux

• Montpellier

• Dothan

• Columbus

• Texarkana

• Ontario

• The Woodlands

• Abilene

Hotels near Landmark

• Albrook Mall

Hotels in District

• Casco Viejo